NIDS-3000 BioThreat Detection Kit | ANP Technologies, Inc.

General Description
The NIDS BioThreat Detection Kit uses next generation multiplexed lateral flow assays to analyze powders and waters for biothreats. Coupled with the handheld reader, results are as accurate as those in a laboratory setting. The assays have 5 targets per ticket, can be stored at room temperature for up to 3 years, and do not suffer from the Hook Effect, a false negative at high concentrations.

Technical Description
The next generation lateral flow assay uses our nano-manipulation technology that orients antibodies on the molecular level so that their biosensing region is always available for sensing, producing a highly sensitive assay that does not suffer from the Hook Effect as traditional lateral flow assays do.

Notes:
This system is the core technology in the DoD's Water Monitoring System.

Evaluation Criteria

THROUGHPUT:

Between 15 and 30 minutes for detection
Multiple samples, single tests/sample per run
349-96 samples every 2 hours
The system could easily be adapted into a fully automated system
Device or system is intended for multiple detection assays
0-1 solutions, buffer, eluents, and/or reagents
2 components
No set-up of the system is required
1-2 steps are required for detection

LOGISTICS:

Very brief (minutes-hours) training and minimal technical skills
Approximately the size of a soda can
Between 1 and 5 kg
Wired connections are available
System or device uses batteries
4-8 hours battery life

OPERATIONS:

Can be used from 4°C to 37°C
Components must be stored at room temperature (27°C)
Performance is not influenced by relative humidity
Between 1 to 3 years shelf life
5-10 years expected life
The system is not capable of autonomy
The system software is closed and not available for modification
The system hardware is closed and not available for modification

DETECTION:

Possible the system could receive 510K clearance, no current efforts at this time
Possible the system could receive FDA approval, no current efforts at this time
Less than 250 µL
Excellent specificity. System has occasional false alarms under certain conditions (<2%)
10,000-100,000 CFU per mL
Greater than 100,000 PFU per mL
1-10 ng per mL
Spore lysis not necessary for detection by system